Pearl
AI company bringing FDA-cleared computer vision to dental radiograph diagnostics
Pearl — About (hellopearl.com)Pearl is an artificial-intelligence company focused on the dental industry, operating at hellopearl.com. Founded in 2019 by Ophir Tanz (Founder & CEO), who previously founded the computer-vision/advertising company GumGum, Pearl is privately held and headquartered in West Hollywood, California, with a workforce in roughly the 51–200 employee range (per its LinkedIn profile).
The company applies machine learning and computer vision to dental x-rays to help dentists detect pathologies and improve diagnostic consistency. Its flagship product, Second Opinion®, is an FDA-cleared AI system that analyzes dental images to flag conditions such as caries, periapical radiolucencies, and bone-level changes for periodontal evaluation. Pearl markets these tools to dental practices and Dental Service Organizations (DSOs) to support clinical decision-making and patient communication.
Pearl has obtained multiple FDA 510(k) clearances and states it became the first dental AI company cleared by the FDA for both 2D and 3D imaging (via Second Opinion® 3D). In July 2024 it announced a $58 million Series B round — reported as the largest of its kind in dental AI — led by Left Lane Capital, with participation from Smash Capital and Alpha Partners. It was named a 2025 Inc. Power Partner Award winner. Reported customers include DSO partners such as Smile Brands.
As an AI-native company built around computer vision for medical imaging, innovation in this space is core to Pearl's business — its products, regulatory clearances, and patent portfolio are the foundation of its market position.